EURO-ECO 2010 Hanover 2 - 3 Dezember 2010	Environmental, Engineering - Economic and Legal Aspects for Sustainable Living
	European Academy of Natural Sciences, Hanover European Scientific Society, Hanover University of Bremen, Bremen

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At the regional level, carried out an epidemiological researching on the contribution of environmental factors in the formation of IDD( iodine deficiency diseases)/

The aim of this work was scientific justification for a system of preventive measures to reduce the risk of iodine deficiency diseases caused by unfavorable environmental factors.

Solve problems in complex hygienic assessment of the habitat 33 municipalities of the region to identify the factors and areas of risk, the prevalence of iodine deficiency disorders among the population with an estimate of their severity, the definition of causation, risk assessment of chronic effects of pollutants on the immune and hormonal system. Final objective of the researching was justification of preventive measures for management decision to reduce the risk of developing iodine deficiency disorders, identifying ways of their implementation and evaluation.

Materials and methods. Performed hygienic assessment antropotehnogennoy burden on the environment based on the regional system of socio-hygienic monitoring. On the dysfunctional area on the level of technogenic load assessed the risk of chronic effects of pollutants on the hormonal environment and the immune system of the population. The are groups of risk. The researching of daily rations of organized groups. The degree of iodine deficiency states in the pilot areas identified by WHO criteria. To quantify the relationship between the level of antropotehnogennoy load and morbidity of the population used correlation analysis.

Results and discussion. Calculation of complex human influence has allowed to identify the territory of risk - Voronezh (SR = 16). Identified chemicals that selectively influence on the hormonal and immune systems, the total hazard index (HI) was 15.9 for the immune system and 1.8 for the hormonal system.

Statistically significant association between the total air pollution (Katm) and endocrine disease (r = 0,63 at p < 0,05); indicators of morbidity diffuse goiter associated with micronutrient deficiency, and manganese concentrations in drinking water (r = 0.23 at p < 0,05).

Laboratory researching 53 daily rations showed a 30% deficiency of iodine in the body with respect to the daily needs.

The results of the pilot epidemiological researchings on the studing of thyroid diseases among children in four districts of the city of Voronezh, and showed that the incidence of endemic goiter greater than sporadic incidence in rural areas from 5 to 12 times, the median urinary iodine varied from 35,0 to 86,0 micrograms per liter. These neonatal screening for congenital hypothyroidism showed that among the examined groups of newborns increased frequencies.

A model of IDD prevention and advice on minimizing the impact of unfavorable factors, and suggestions made in the regional target program. Economic efficiency by preventing 460 new cases for the city of Voronezh was 2.5 million rubles.