EURO-ECO 2009 Hanover 3 - 4 Dezember 2009	Environmental, Engineering - Economic and Legal Aspects for Sustainable Living
	European Academy of Natural Sciences, Hanover European Scientific Society, Hanover University of Bremen, Bremen

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Abstracts EURO-ECO 2009

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M.I. Shtilman

Polyvinylpyrrolidone is the most common synthetic drug polymer, which is the component of blood substitutes, the carriers for different low molecular weight bioactive and drug substances as well as the component of other drug formulations. The polymer is a commercial product in many countries, and its commercial modifications (such as Hemodes, Povidone, Kollidon) have a wide medicinal applications.

Introduction of various functional groups in polyvinylpyrrolidone substantially change its properties. The study deals with the development of several novel methods of chemical modification of polyvinylpyrrolidone’s structure. The modified polymers exhibit various types of bioactivity such as immunoactivity, anticancer and antiviral effect, etc.

It has been proved that amphiphilic derivatives of polyvinylpyrrolidone is able to protect liposomal formulations, In water media they generate nano-sized aggregates which can immobilized different drugs and convert them in completely soluble systems.

Moreover additional reactive chemical groups provide polymers’ transportation to the damaged organs in liquid media.

It has been demonstrated that these nano-aggregates can be used for production of harmless formulations for agriculture.